MitochondriaLongevity

SS-31 (Elamipretide)

Mitochondrial-Targeted Peptide

Typical Dose

1–5 mg

Route

Injectable

Variants

30mg

Overview

What is SS-31 (Elamipretide)?

SS-31 (elamipretide) is a tetrapeptide that targets the inner mitochondrial membrane, binding cardiolipin to stabilize mitochondrial structure and function.

Mechanism of Action

Binds cardiolipin, preserves electron transport chain efficiency, reduces ROS and supports ATP production.

Key Benefits

Improves mitochondrial efficiency
Reduces oxidative stress
Supports cardiac and muscle function

Research Indications

Mitochondrial dysfunctionMost Effective

Heart failure researchEffective

Age-related fatigueEffective

Research Protocols

Disclaimer

These are commonly discussed research protocols and not medical advice. Consult a healthcare provider before use.

Goal	Dose	Frequency	Route
Conservative	1 mg	1x daily	Subcutaneous
Standard starting dose	2 mg	1x daily	Subcutaneous
Typical maintenance	3 mg	1x daily 5/7	Subcutaneous
Maximum	5 mg	1x daily	Subcutaneous

Peptide Interactions

MOTS-c

Synergistic

NAD+

Synergistic

Side Effects & Safety

Common Side Effects

Injection-site reaction
Headache
Generally well tolerated

Safety Guidelines

For laboratory research use only — not for human consumption
Store reconstituted vials at 2–8°C, use within 30 days
Rotate injection sites to avoid local irritation
Discontinue and consult a clinician if adverse reactions occur

Quality Indicators

≥95% purity verified by HPLC
Third-party tested for sterility
Lyophilized in sealed multi-dose vial
Bacteriostatic water reconstitution
Refrigerated cold-chain shipping

What to Expect

1
Week 1–2
Energy uplift
2
Week 3–6
Endurance and recovery gains
3
Week 7–12
Sustained mitochondrial benefits

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