Overview
What is Semax?
Semax is a Russian-developed ACTH(4-10) analog used in research for cognitive enhancement, neuroprotection, and stroke recovery.
Mechanism of Action
Upregulates BDNF and NGF, modulates dopamine and serotonin systems, neuroprotective via antioxidant action.
Key Benefits
- Improved focus and memory
- Neuroprotection
- Mood support
Research Indications
Cognitive enhancementMost Effective
Neuroprotection / strokeEffective
ADHD-type focus supportEffective
Research Protocols
Disclaimer
These are commonly discussed research protocols and not medical advice. Consult a healthcare provider before use.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Conservative | 300 mcg | 1x daily | Nasal |
| Standard starting dose | 600 mcg | 1x daily | Nasal |
| Typical maintenance | 600 mcg | 2x daily | Nasal |
| Maximum | 900 mcg | 2x daily | Nasal |
Peptide Interactions
Selank
Stimulants
Side Effects & Safety
Common Side Effects
- Nasal irritation
- Headache
- Overstimulation if dosed late
Safety Guidelines
- For laboratory research use only — not for human consumption
- Store reconstituted vials at 2–8°C, use within 30 days
- Rotate injection sites to avoid local irritation
- Discontinue and consult a clinician if adverse reactions occur
Quality Indicators
- ≥95% purity verified by HPLC
- Third-party tested for sterility
- Lyophilized in sealed multi-dose vial
- Bacteriostatic water reconstitution
- Refrigerated cold-chain shipping
What to Expect
- 1Day 1Sharper focus within hours
- 2Week 1Sustained cognitive uplift
- 3Week 2–4Neuroprotective benefits accrue
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