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LongevityEnergyMitochondria
NAD+
Cellular Energy & Longevity Cofactor
Typical Dose
50–500 mg
Route
Injectable
Variants
500mg · 1000mg
Overview
What is NAD+?
Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme for cellular energy production, DNA repair and sirtuin activity, declining with age.
Mechanism of Action
Substrate for sirtuins, PARPs and CD38, supporting mitochondrial respiration and DNA repair pathways.
Key Benefits
- Boosts cellular energy
- Supports DNA repair
- Activates sirtuin longevity pathways
- Mental clarity
Research Indications
Cellular agingMost Effective
Energy and cognitionEffective
Addiction recovery researchModerate
Research Protocols
Disclaimer
These are commonly discussed research protocols and not medical advice. Consult a healthcare provider before use.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Conservative | 50 mg | 2x weekly | Subcutaneous (slow) |
| Standard starting dose | 100 mg | 2x weekly | Subcutaneous |
| Typical maintenance | 100–200 mg | 3x weekly | Subcutaneous |
| Maximum | 500 mg | 1x weekly IV | IV (clinical only) |
Peptide Interactions
MOTS-c
Epithalon
Resveratrol
Side Effects & Safety
Common Side Effects
- Flushing during injection
- Chest tightness if pushed fast
- Nausea
Safety Guidelines
- For laboratory research use only — not for human consumption
- Store reconstituted vials at 2–8°C, use within 30 days
- Rotate injection sites to avoid local irritation
- Discontinue and consult a clinician if adverse reactions occur
Quality Indicators
- ≥95% purity verified by HPLC
- Third-party tested for sterility
- Lyophilized in sealed multi-dose vial
- Bacteriostatic water reconstitution
- Refrigerated cold-chain shipping
What to Expect
- 1Day 1–3Immediate energy uplift
- 2Week 1–2Improved focus and mood
- 3Week 3–8Sustained cellular benefits
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