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GutSkinHealingAnti-inflammatory
KPV
α-MSH Tripeptide | Anti-inflammatory
Typical Dose
200–500 mcg daily
Route
Injectable
Price (AUD)
$120
Vial size
Bundle & Supplies
Add-on · Recommended
Pre-filled Disposable Pen
Your compound pre-loaded into a sterile, single-patient disposable injection pen. Eliminates vial reconstitution and syringe drawing. Twist the dose dial, press, done.
Disposable penDial-a-doseSealed sterile
Upgrade Price
+$50
Overview
What is KPV?
KPV is the C-terminal tripeptide (Lys-Pro-Val) of α-MSH, studied for its potent anti-inflammatory action in the gut, skin and connective tissue — without the pigmentation effects of full α-MSH.
Mechanism of Action
Inhibits NF-κB signaling and pro-inflammatory cytokine production (TNF-α, IL-1β, IL-6), reduces mast cell degranulation, and supports mucosal barrier integrity.
Key Benefits
- Down-regulates systemic and gut inflammation
- Supports gut-lining repair (IBD/colitis research)
- Calms inflammatory skin conditions
- Synergistic with BPC-157 and TB-500 for healing
Research Indications
Inflammatory bowel researchMost Effective
Eczema, psoriasis, dermatitisEffective
Mast cell / allergic inflammationEffective
Wound healingModerate
Research Protocols
Disclaimer
These are commonly discussed research protocols and not medical advice. Consult a healthcare provider before use.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Conservative | 200 mcg | 1x daily | Subcutaneous or oral capsule |
| Standard starting dose | 300 mcg | 1x daily | Subcutaneous |
| Typical maintenance | 500 mcg | 1x daily | Subcutaneous |
| Maximum | 500 mcg | 2x daily | Subcutaneous |
Peptide Interactions
BPC-157
Gut + soft-tissue healing stack
TB-500
KLOW
KPV is already a component
Immunosuppressants
Side Effects & Safety
Common Side Effects
- Generally very well tolerated
- Mild injection-site reaction
- Rare transient headache
Safety Guidelines
- For laboratory research use only — not for human consumption
- Store reconstituted vials at 2–8°C, use within 30 days
- Rotate injection sites to avoid local irritation
- Discontinue and consult a clinician if adverse reactions occur
Quality Indicators
- ≥99% purity verified by HPLC
- Third-party tested for sterility
- Lyophilized in sealed multi-dose vial
- Bacteriostatic water reconstitution
- Refrigerated cold-chain shipping
What to Expect
- 1Week 1Reduced inflammatory symptoms
- 2Week 2–4Gut and skin improvements
- 3Week 5–8Sustained mucosal and barrier repair
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